Knowledge Diamonds: April 2008 Archives

Women who eat diets similar to the Dietary Approaches to Stop Hypertension (DASH) diet--which is low in animal protein, moderate in low-fat dairy products and high in plant proteins, fruits and vegetables--appear to have a lower risk of coronary heart disease and stroke, according to a new report.

The DASH diet has been shown to reduce both systolic (top number) and diastolic (bottom number) blood pressure in individuals with high or normal blood pressure, according to background information in the article. The diet has also been shown to reduce low-density lipoprotein ("bad") cholesterol and is recommended in national dietary guidelines as an example of a healthy eating pattern.

Teresa T. Fung, Sc.D., of Simmons College, Boston, and colleagues studied 88,517 female nurses age 34 to 59 in the Nurses' Health Study who did not have cardiovascular disease or diabetes in 1980. Seven times from 1980 through 2004, the women reported the types of foods they ate regularly over the previous year. Researchers then calculated a DASH score for each woman based on eight food and nutrient components. Their scores increased when they ate more fruits, vegetables, whole grains, nuts and legumes and stayed close to the recommended amounts of low-fat dairy. Scores decreased with increased consumption of red and processed meats, sweetened beverages and sodium.

Nanomachine Kills Cancer Cells

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james_clerk_maxwell.jpgResearchers from the Nano Machine Center at the California NanoSystems Institute at UCLA have developed a novel type of nanomachine that can capture and store anticancer drugs inside tiny pores and release them into cancer cells in response to light.

Known as a "nanoimpeller," the device is the first light-powered nanomachine that operates inside a living cell, a development that has strong implications for cancer treatment.

UCLA researchers reported the synthesis and operation of nanoparticles containing nanoimpellers that can deliver anticancer drugs in the journal Small.

Nanomechanical systems designed to trap and release molecules from pores in response to a stimulus have been the subject of intensive investigation, in large part for their potential applications in precise drug delivery. Nanomaterials suitable for this type of operation must consist of both an appropriate container and a photo-activated moving component.
 

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This page is a archive of entries in the Knowledge Diamonds category from April 2008.

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